Research
Dr Louise Segan’s research focuses on improving outcomes for patients with heart rhythm disorders, particularly atrial fibrillation and heart failure. Through clinical and translational research, her work aims to refine treatment strategies and highlight the role of lifestyle modification in long-term rhythm management, ensuring that patient care is informed by the latest evidence.
Prognostic impact of diagnosis-to-ablation time on outcomes following catheter ablation in persistent atrial fibrillation and left ventricular systolic dysfunction
Heart Rhythm. 2025 Jun;22(6):1429–1436.
Segan L et al. – Examines timing of AF ablation and clinical outcomes.
Persistent Atrial Fibrillation Phenotypes and Ablation Outcomes: Persistent From Outset vs Progression From Paroxysmal AF
JACC: Clinical Electrophysiology (2025;11(1):10–18)
Crowley R, Chieng D, Segan L et al. – Analysis of AF phenotypes and post-ablation results.
Sex-specific outcomes following catheter ablation in persistent AF
Heart Rhythm (2024 Jun;21(6):762–770)
Segan L et al. – Assesses differences in ablation outcomes by sex.
Posterior Wall Isolation Improves Outcomes for Persistent AF With Rapid Posterior Wall Activity: CAPLA Substudy
JACC: Clinical Electrophysiology (2023;9(12):2536–2546)
Segan L et al. – Substudy of adjunctive posterior wall isolation in AF.
Impact of Posterior Left Atrial Voltage on Ablation Outcomes in Persistent Atrial Fibrillation: CAPLA Substudy
JACC: Clinical Electrophysiology (2023;9(11):2291–2299)
Chieng D, Segan L et al. – Voltage-guided ablation insights.
Impact of Baseline Left Atrial Size on Outcomes Following Catheter Ablation for AF in Patients with Left Ventricular Systolic Dysfunction
Circulation: Arrhythmia and Electrophysiology (2024;17(5))
Segan L et al. – Explores left atrial size influence on AF ablation outcomes.
Higher Power Short Duration vs. Lower Power Longer Duration Posterior Wall Ablation for Atrial Fibrillation and Oesophageal Injury Outcomes: Hi-Lo HEAT trial
EP Europace (2022)
Segan L et al. – Randomised study of ablation energy strategies.
The fa(r)st or the spurious — pulmonary vein cycle length and persistent AF mechanisms
Journal of Cardiovascular Electrophysiology (2022)
Segan L et al. – Commentary on AF electrophysiology.
Atrial Fibrillation and Stress: A 2-Way Street?
JACC: Clinical Electrophysiology (2022)
Segan L, Prabhu S, Kalman JM, Kistler PM – Review of stress and AF interactions.
Catheter ablation for persistent AF: multicentre randomised trial of pulmonary vein isolation vs PVI with posterior wall isolation — the CAPLA study
American Heart Journal (2021)
Segan L et al. – Multicentre AF ablation trial.
Long-term outcomes of index cryo-balloon ablation or point-by-point radiofrequency ablation in AF and systolic heart failure
Journal of Cardiovascular Electrophysiology (2021)
Segan L et al. – Comparative ablation outcomes.
Incidence of premature lead failure in pacing leads: single-centre experience
Heart Lung Circulation (2020)
Segan L et al. – Pacemaker lead reliability study.
Learn More About Dr Segan
To learn more about Dr Louise Segan’s clinical background and approach to care, please visit the About page.
Details on training, research, and hospital appointments are available there.